Article ID Journal Published Year Pages File Type
6795192 Hormones and Behavior 2011 9 Pages PDF
Abstract
► Lordosis requires deactivation of medial preoptic nucleus μ-opioid receptors (MOP). ► Estradiol-only (E) acts through orphanin FQ activation of ORL-1 to deactivate MOP. ► Estradiol + progesterone (E + P) MOP deactivation does not require orphanin FQ. ► E and E + P signaling converges on arcuate nucleus β-endorphin neurons. ► E and E + P use different neurotransmitters to inhibit MOP and facilitate lordosis.
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