Accumbal dopamine function in postpartum rats that were raised without their mothers

► Early preweaning experiences have long-term effects on later mothering behavior. ► Compared to controls, postpartum and hormone-treated females have reduced basal DA and elevated pup-evoked DA responses. ► Rats raised without their mother had impaired basal DA suppression and pup-evoked DA responses. ► Hormone-treatment in OVX rats and tactile stimulation in cycling or parturient rats prevents impairment.