Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6800886 | Journal of Psychiatric Research | 2014 | 7 Pages |
Abstract
The elasticity in diurnal serum BDNF variation is associated with favourable treatment response to PSD in patients suffering from MDD. Therefore, a normalized BDNF serum profile which oscillates in a circadian fashion seems to precede, rather than follow a favourable treatment outcome in depressed patients. Furthermore the fast increase of BDNF is comparable to effects seen with ketamine infusion.
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Authors
Maria Giese, Johannes Beck, Serge Brand, Flavio Muheim, Ulrich Hemmeter, Martin Hatzinger, Edith Holsboer-Trachsler, Anne Eckert,