Article ID Journal Published Year Pages File Type
68031 Journal of Molecular Catalysis A: Chemical 2007 9 Pages PDF
Abstract

The kinetics of vinylation of 4′-bromoacetophenone (4′-BAP) with n-butyl acrylate (n-BA) has been studied using palladacycle catalyst precursor 1, in the presence of sodium acetate (NaOAc) as a base and tetrabutylammonium bromide (TBAB) as a promoter in N-methyl-2-pyrrolidinone (NMP) solvent. The rate was found to be first order with respect to 4′-BAP, fractional order with the catalyst, and first order tending to zero order with NaOAc concentration. The rates passed through a maximum with variation of TBAB and n-butyl acrylate concentrations. The rate data have been analyzed to propose an empirical model, which is in good agreement with the mechanism already established for Heck reactions using palladacycle catalysts.

Graphical abstractThe kinetics of vinylation of 4′-bromoacetophenone with n-butyl acrylate has been studied using palladacycle catalyst precursor 1, in the presence of NaOAc as a base and tetrabutylammonium bromide as a promoter in N-methyl-2-pyrrolidinone as solvent. The rate of reaction was found to be first order with respect to 4′-BAP, half order with the catalyst, and first order tending to zero with NaOAc concentration. The rates passed through a maximum with variation of TBAB and n-butyl acrylate concentrations. The rate data have been analyzed to propose an empirical model, which is consistent with the mechanism already established for Heck reactions. Figure optionsDownload full-size imageDownload as PowerPoint slide

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Physical Sciences and Engineering Chemical Engineering Catalysis
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