Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6809909 | Neurobiology of Aging | 2012 | 15 Pages |
Abstract
Baseline measures of brain structure and tissue pathology predicted rate of cognitive decline in a diverse and carefully characterized cohort, suggesting that they may provide summary measures of pre-existing neuropathological damage or the capacity of the brain to compensate for the impact of subsequent neuropathology on cognition. Conventional MRI measures may have use for predicting cognitive outcomes in highly heterogeneous elderly populations.
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Authors
Owen Carmichael, Dan Mungas, Laurel Beckett, Danielle Harvey, Sarah Tomaszewski Farias, Bruce Reed, John Olichney, Joshua Miller, Charles DeCarli,