Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
68104 | Journal of Molecular Catalysis A: Chemical | 2007 | 6 Pages |
Molecular iodine has been used an efficient catalyst for an improved and rapid one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetra substituted imidazoles in excellent yields. The significant features of the iodine-catalyzed condensation are operational simplicity, inexpensive reagents, high yield of products and the use of non-toxic reagents.
Graphical abstractMolecular iodine has been used as an efficient catalyst for an improved and rapid one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles in excellent yields. The significant features of the iodine-catalyzed condensation are operational simplicity, inexpensive reagents, high yield of products and the use of non-toxic reagents. Figure optionsDownload full-size imageDownload as PowerPoint slide