Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6811503 | Psychiatry Research | 2018 | 19 Pages |
Abstract
Continuous aerobic exercise training (CAT) is considered a complementary treatment option in patients with major depressive disorder (MDD). Intermittent exercise training protocols, such as sprint interval training (SIT) have gained increasing popularity, but no studies on depressive symptoms following SIT in patients with MDD are available. Fifty-nine in-patients with MDD were randomly assigned to a SIT or CAT group. Medication was counterbalanced in both intervention arms. Both intervention groups received 3 weekly training sessions for 4-weeks (12 sessions in total). SIT comprised 25 bouts of 30 seconds at 80% of maximal power, whereas CAT consisted of 20 minutes of physical activity at 60% of maximal power. The training protocols were isocalorically designed. Maximal bicycle ergometer exercise testing yielded maximal and submaximal physical fitness parameters. The Beck-Depression-Inventory-II (BDI-II) was filled out by the patients before and after the intervention period. BDI-II scores substantially decreased in both groups with an effect size pointing towards a large effect (pâ¯<â¯0.001, ηp²â¯=â¯0.70) while submaximal (0.07â¯<â¯dâ¯<â¯0.89) and maximal (0.05â¯<â¯dâ¯<â¯0.85) fitness variables improved in both groups. Short-term SIT leads to similar results as CAT in patients with MDD and can be regarded as a time-efficient and promising exercise-based treatment strategy.
Keywords
Sprint interval trainingBDI-IIVO2peakRCTVCO2RERSITMDDVO2CATRPMBDNFHRVRandomized controlled trialDepressive disorderMajor depressive disorderHITDepressionInpatientIntermittent exerciseHigh intensity interval trainingExercise trainingOxygen uptakeMaximal oxygen uptakecarbon dioxide outputrevolutions per minutebody mass indexBMIHeart rateBrain-derived neurotrophic factorrespiratory frequencyInterval trainingRespiratory exchange ratioheart rate variabilityBeck Depression InventoryVentilatory efficiency
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Authors
Alice Minghetti, Oliver Faude, Henner Hanssen, Lukas Zahner, Markus Gerber, Lars Donath,