| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 68118 | Journal of Molecular Catalysis A: Chemical | 2007 | 4 Pages |
Abstract
Polyethylene glycol (PEG) in water is found to be an inexpensive, non-toxic and eco-friendly reaction medium for the nucleophilic addition of trimethylsilyl cyanide (TMSCN) to imines (Strecker reaction) to afford α-aminonitriles in excellent yields. This protocol is effective to a wide variety of substrates with different functional groups and does not require the use of acid or base catalyst. PEG can be recovered and reused.
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Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
M. Anil Kumar, M.F. Stephen Babu, K. Srinivasulu, Y.B. Kiran, C. Suresh Reddy,