Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6812568 | Psychiatry Research | 2016 | 4 Pages |
Abstract
Early onset of heroin use is a severity marker of heroin use disorder. We studied the interaction between early onset and rapid transition to heroin dependence recorded with retrospective interviews in 213 patients with severe heroin dependence and history of methadone maintenance treatment. General linear models were used to identify independent factors associated with early onset, factors associated with rapid transition to dependence, and a multivariate model was used to study the interaction of those two dimensions. Lifetime history of anxiety disorders and age at onset of cannabis use are shared common risk factors and are associated with the interaction.
Related Topics
Life Sciences
Neuroscience
Biological Psychiatry
Authors
Emily Karsinti, Maeva Fortias, Gaël Dupuy, Kamilia Ksouda, Xavier Laqueille, Anne-Marie Simonpoli, Didier Touzeau, Elisabeth Avril, Cyrille Orizet, Beatriz Belforte, Philippe Coeuru, Pierre Polomeni, Romain Icick, Marine Jarroir, Vanessa Bloch,