Interaction of isothermal phase inversion and membrane formulation for pathogens detection in water

The aim of this study was to explore the utilization of polymeric membrane for bio-sensing application in most efficient and rapid way. Customization of membrane formulation via phase separation study to modify its morphologies and properties enable the detection of different pathogens in a specific manner. Experimental findings (FESEM, through-pore distribution, porosity, capillary flow test and protein binding test) verified the predictions of faster capillary flow time and higher membrane’s protein binding by the addition of cellulose acetate and nitrocellulose to the membrane casting dope, respectively. Throughout the phase separation study, the potential phase behavior was investigated, which was correlating various membrane structures to its performances for potential pathogens detection in water.

► Synthesize lateral flow membrane for potential pathogens detection in drinking water. ► Correlate membrane morphologies to its bio-sensing performances. ► Biosensor performances on protein binding and lateral diffusion studies.