Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6817578 | Psychoneuroendocrinology | 2018 | 6 Pages |
Abstract
Given the limitations of the study, we could show that the therapeutic response to a multimodal treatment in clinically depressed patients not receiving cytokine treatment is associated with changes in Kyn levels and the Kyn/Trp ratio as well as with hsCRP. However, it is too early to draw any causal conclusion. Future research should clarify relevant clinical and neurobiological parameters associated with changes in Kyn levels and Kyn/Trp ratio, especially in regard to clinical response.
Keywords
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Authors
B. Reininghaus, K. Riedrich, N. Dalkner, S.A. Bengesser, A. Birner, M. Platzer, C. Hamm, J.M. Gostner, D. Fuchs, E.Z. Reininghaus,