Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6817855 | Psychoneuroendocrinology | 2018 | 10 Pages |
Abstract
In conclusion, an endogenous cannabinoid tone maintains the HPA axis in a stable basal state, which is lost with a noxious stimulus. In this case, the ECS dampens the response to stress allowing the recovery of homeostasis. Moreover, our work further contributes to in vitro evidence for a participation of the endocannabinoid system by inhibiting corticosterone release directly at the adrenal gland level.
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Authors
Pablo Nicolás Surkin, Sofia Ludmila Gallino, Valeria Luce, Fernando Correa, Javier Fernandez-Solari, Andrea De Laurentiis,