Article ID Journal Published Year Pages File Type
6818554 Psychoneuroendocrinology 2015 6 Pages PDF
Abstract
The inverse relationship between plasma MR-proADM and anxiety observed in patients with cardiovascular risk factors supports a previous experimental study using a mutant mouse line with a brain-specific loss of ADM expression which displayed hyperactive and over-anxious behavior. Further experimental and clinical studies are warranted to test the hypothesis that also in humans ADM acts as a neuromodulator with anxiolytic properties.
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Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
Preview
Plasma mid-regional pro-adrenomedullin levels are inversely associated with anxiety but unrelated to depression: Results from the observational DIAST-CHF study in patients with cardiovascular risk factors
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