Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6819005 | Psychoneuroendocrinology | 2015 | 10 Pages |
Abstract
Several associations, which differed across the genders, were observed between IGF-1 and depression. Cross-sectional findings were not supported by longitudinal findings, which suggest that IGF-1 may not play an important predictive role in the development of depression in older persons over time. However, a more acute role of IGF-1 in current depression, as indicated by the cross-sectional results, may be possible. Further studies are needed to elucidate the complex relation between IGF-1 and late-life depression.
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Authors
N.C. van Varsseveld, C.C. van Bunderen, E. Sohl, H.C. Comijs, B.W.J.H. Penninx, P. Lips, M.L. Drent,