Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6819315 | Psychoneuroendocrinology | 2015 | 11 Pages |
Abstract
In conclusion, paroxetine seems to interfere with HPA-axis dysregulation, reflected in significant overall decreases in BCL and AUC during treatment. Paroxetine appears to decrease HPA-axis set-point in MDD, which might result in increased HPA-axis activity over time, which is further improved when patients achieve remission (ISRCTN register nr. ISRCTN44111488).
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Authors
Henricus G. Ruhé, Sharina J. Khoenkhoen, Koen W. Ottenhof, Maarten W. Koeter, Roel J.T. Mocking, Aart H. Schene,