| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6829702 | Seizure | 2018 | 7 Pages |
Abstract
The functional right hippocampus-cerebellum circuit might contribute to the pathogenesis of depressive symptoms in epilepsy, with the exception of brain areas associated with emotion such as the frontal and temporal lobes. Modulating the hippocampus-cerebellum circuit is a potential therapeutic strategy for epilepsy patients with depressive symptoms.
Keywords
ACCBPRSOXCVPALTGGTCSReHoCZPAEDs1H-MRSTLEMMSETPMPHTMDDCbzROIFunctional connectivityMajor depressive disorderDepressionMRIstandard deviationOxcarbazepinestatus epilepticusEpilepsyFocal seizureMagnetic resonance imagingResting state functional magnetic resonance imagingfMRIfunctional magnetic resonance imagingPositron emission tomographyTopiramateHAMD-17Valproatetemporal lobe epilepsyPhenobarbitalPhenytoinanterior cingulate cortexLamotrigineCerebellum17-item Hamilton depression rating scaleBrief Psychiatric Rating Scaleregion of interestRegional homogeneityHippocampusPETcarbamazepineClonazepamhealthy controls
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Authors
Weifeng Peng, Lingyan Mao, Dazhi Yin, Wei Sun, He Wang, Qianqian Zhang, Jing Wang, Caizhong Chen, Mengsu Zeng, Jing Ding, Xin Wang,