| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6829801 | Seizure | 2018 | 4 Pages |
Abstract
An increase in the total VPA concentration results in corresponding linear and non-linear rise in the VPA free fraction and free VPA concentration, respectively. The total daily dose of VPA should be increased in smaller increments whenever a total VPA concentration of 60â¯Î¼g/mL is reached. When drug monitoring is needed, we recommend measuring the free VPA concentration. If this test is unavailable, and for patients with normal albumin levels, it can be predicted from the total VPA concentration using the generated equation.
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Authors
Wassim Nasreddine, Maya Dirani, Samir Atweh, Achraf Makki, Ahmad Beydoun,