| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6830085 | Seizure | 2018 | 6 Pages |
Abstract
The intronic rs6730344, rs6732655 and rs10167228 polymorphisms of the SCN1A gene are a potential risk factors for drug resistance. AA e AT genotype of the rs1962842 intronic polymorphism also emerged as a risk factor in the drug resistant group. Therefore, polymorphisms of the SCN1A gene could play a role in the response to AED in patients with drug-resistant epilepsy, with important implications for clinical practice.
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Authors
Lucia Margari, Anna R. Legrottaglie, Alessandra Vincenti, Giangennaro Coppola, Francesca F. Operto, Maura Buttiglione, Amalia Cassano, Nicola Bartolomeo, Maria A. Mariggiò,