Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6830433 | Seizure | 2016 | 6 Pages |
Abstract
Higher-evening differential dose of clobazam improved seizure control in patients with predominantly nighttime and early-morning seizures. Chronotherapy tailored to the patients' seizure susceptibility patterns may improve care in epilepsy patients as differential dosing may allow for higher overall treatment doses at times of greatest seizure susceptibility without increased side effects at other times.
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Authors
Sigride Thome-Souza, Jacquelyn Klehm, Michele Jackson, Navah E. Kadish, Sheryl Manganaro, Iván Sánchez Fernández, Tobias Loddenkemper,