Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6830611 | Seizure | 2016 | 5 Pages |
Abstract
The most effective drugs in patients with PCDH19 mutations were bromide and clobazam. Although epilepsy in PCDH19 mutations is often pharmacoresistant, three quarters of the patients became seizure-free for at least for 3 months and half of them for at least one year. However, assessing the effectiveness of the drugs is difficult because a possible age-dependent spontaneous seizure remission must be considered.
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Authors
Jan Lotte, Thomas Bast, Peter Borusiak, Antonietta Coppola, J. Helen Cross, Petia Dimova, Andras Fogarasi, Irene GraneÃ, Renzo Guerrini, Helle Hjalgrim, Reinhard Keimer, Christian M. Korff, Gerhard Kurlemann, Steffen Leiz, Michaela Linder-Lucht,