| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 68335 | Journal of Molecular Catalysis A: Chemical | 2006 | 4 Pages |
Abstract
3-Bromopyridine-4-carbaldehyde is tethered with suitably electron withdrawing group substituted alkenes via Heck coupling followed by aldol reaction in dioxane at 150 °C under a catalytic system of Pd(OAc)2/PPh3/NaOAc to afford the corresponding isoquinolines in good yields.
Graphical abstract3-Bromopyridine-4-carbaldehyde is cyclized with suitably electron withdrawing group substituted alkenes in the presence of a palladium catalyst to give isoquinolines. Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Chan Sik Cho, Daksha B. Patel,