| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 68421 | Journal of Molecular Catalysis A: Chemical | 2006 | 5 Pages |
The Ullmann coupling of amines with aryl iodide and bromides has been carried out efficiently using Pd(OAc)2/1,2-bis(diphenylphosphino) ethane [DPPE] in toluene as a solvent. The effects of various parameters such as temperature, solvent, base, catalyst loading and metal–ligand ratio on the reaction system were studied. The reaction is applicable to a wide variety of substituted aryl amines and alkyl amines with different steric and electronic properties.
Graphical abstractThe Ullmann coupling of amines with aryl iodide and bromides has been carried out efficiently using Pd(OAc)2/1,2-bis(diphenylphosphino) ethane [DPPE] in toluene as a solvent. The effects of various parameters such as temperature, solvent, base, catalyst loading and metal–ligand ratio on the reaction system were studied. The reaction is applicable to a wide variety of substituted aryl amines and alkyl amines with different steric and electronic properties. Figure optionsDownload full-size imageDownload as PowerPoint slide
