| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 68545 | Journal of Molecular Catalysis A: Chemical | 2006 | 5 Pages |
Tandem Friedel–Crafts reaction of arenes and aldehydes under the catalysis of Lewis acid was investigated. Both aromatic and aliphatic aldehydes underwent a tandem Friedel–Crafts alkylation with electron-rich arenes to afford 1,1,1-triaryl/1,1-diarylalkanes in the presence of anhydrous aluminum chloride under solvent-free conditions. The scope, limitation, and mechanism of the tandem reaction were also discussed.
Graphical abstractTandem Friedel–Crafts reaction of arenes and aldehydes under the catalysis of Lewis acid was investigated. Both aromatic and aliphatic aldehydes underwent a tandem Friedel–Crafts alkylation with electron-rich arenes to afford 1,1,1-triaryl/1,1-diarylalkanes in the presence of anhydrous aluminum chloride under solvent-free conditions.Figure optionsDownload full-size imageDownload as PowerPoint slide
