Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
68595 | Journal of Molecular Catalysis A: Chemical | 2006 | 5 Pages |
Enantioselective reductions of a variety of aromatic ketones catalyzed by [RuCl2(p-cymene)]2 coordinated by N-phenyl-(l)-proline amide in water have been performed with high asymmetric inductions in several cases. The reusability of catalyst has been studied. A multi-substrate recycling of the catalyst afforded successively seven alcohols each with similar enantiomeric excess than the one recorded in a single run.
Graphical abstractEnantioselective reductions of a variety of aromatic ketones have been performed with high asymmetric inductions in several cases. A multi-substrate recycling of the catalyst afforded successively seven alcohols each with similar enantiomeric excess than the one recorded in a single run. Figure optionsDownload full-size imageDownload as PowerPoint slide