Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6877628 | Journal of Molecular Graphics and Modelling | 2015 | 39 Pages |
Abstract
For the first time we report a novel mechanism that governs the recognition of avirulence protein avrxa5 from pathogen Xoo by eukaryotic transcription factor xa5 of rice. The C-terminal end of xa5 is deeply buried inside the cavity of helical region of C-terminal end of avrxa5 and reinforced by H-bonds and electrostatic interactions contributing towards the molecular recognition process. Further binding free energy analysis showed polar solvation energy contributed more than three fold of the non-polar solvation terms towards molecular recognition.
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Authors
Budheswar Dehury, Jitendra Maharana, Bikash Ranjan Sahoo, Jagajjit Sahu, Priyabrata Sen, Mahendra Kumar Modi, Madhumita Barooah,