| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6877641 | Journal of Molecular Graphics and Modelling | 2015 | 31 Pages |
Abstract
D2, D3, D4 and 5-HT2A receptors were modeled and refined by molecular dynamics simulations. Docking studies show the correlations between computed and experimental pKi is matched well. The homology models can be used as 3D templates for antipsychotic drug design and virtual screening in the future.
Related Topics
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Chemistry
Physical and Theoretical Chemistry
Authors
Xinli Duan, Min Zhang, Xin Zhang, Fang Wang, Ming Lei,