| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6877663 | Journal of Molecular Graphics and Modelling | 2015 | 51 Pages |
Abstract
- In silico comparative analysis of ribose 5-phosphate isomerase (R5PI) type A and B.
- 3D model construction of analogous Leishmania major and Homo sapiens R5PI.
- 3D models were constructed combining comparative and ab initio modeling techniques.
- Active site characterization based on docking studies of the substrates R5P and 5RP.
- We propose two distinct reaction mechanisms (R5Pâ5RP) catalyzed by LmRpiB and HsRpiA.
Related Topics
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Authors
Priscila V.S.Z. Capriles, Luiz Phillippe R. Baptista, Isabella A. Guedes, Ana Carolina R. Guimarães, Fabio L. Custódio, Marcelo Alves-Ferreira, Laurent E. Dardenne,