Models for H3 receptor antagonist activity of sulfonylurea derivatives

- In the present study, a wide variety of 2D and 3D molecular descriptors (MDs) were successfully utilized for the development of models.
- Accuracy of prediction of proposed models developed through decision tree, random forest and moving average analysis varied from 88% to 95%.
- Proposed models offer vast potential for providing lead structures for development of potent but safe H3 receptor antagonist sulfonylurea derivatives.