Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
688270 | Chemical Engineering and Processing: Process Intensification | 2013 | 9 Pages |
Abstract
Four commercial nanofiltration membranes were studied in a stirred dead-end filtration module, i.e. NF 90, NF 270, Duramem 150 and BW30XLE, supplied by Evonik Industries and Filmtec (Dow). The membranes Duramem 150 and NF 90 showed the best performance, allowing a recovery of G-1 of above 60% in one stage. The separation factor of pyridine/G-1 for Duramem 150 and NF 90 was found to be higher than 2 for synthetic mixtures containing 26.75Â g/L of G-1, 5.35Â g/L of pyridine, 0.149Â g/L of bromine and 0.105Â g/L of acetic anhydride in ethanol. It was found that when using dead-end filtration, the recovery of G-1 is low when a high purity is required; both parameters cannot be optimized together. However, it is shown that with a sequence of filtrations, the recovery can be significantly improved at a given purity of G-1. These results indicate that the application of organic solvent nanofiltration for the recycling of valuable pharmaceutical compounds is feasible in realistic conditions.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Process Chemistry and Technology
Authors
M. Brito MartÃnez, N. Jullok, Z. Rodriguez Negrin, B. Van der Bruggen, P. Luis,