Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
68945 | Journal of Molecular Catalysis A: Chemical | 2006 | 5 Pages |
Abstract
A simple method for the one-pot, three-component Biginelli condensation reaction of 5-chloro/phenoxyl-3-methyl-1-phenyl-4-formylpyrazole, a 1,3-dicarbonyl compound and urea or thiourea is described, employing Magnesium perchlorate [Mg(ClO4)2] as an efficient catalyst under ultrasound irradiation. A novel series of 4-substituted pyrazolyl-3,4-dihydropyrimidin-2(1H)-(thio)ones have been synthesized in moderate yields. The catalyst exhibited remarkable reactivity and can be recycled.
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Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Xinli Zhang, Yanping Li, Chenjiang Liu, Jide Wang,