Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6972241 | Journal of Hazardous Materials | 2013 | 10 Pages |
Abstract
⺠Validated for the first time a hanging drop (HD) air toxic exposure method for inhalation exposures effect studies. ⺠Applied a four compartment mass balance model to calculate cellular exposure levels. ⺠Compared A549 2-dimentional (2D) cell culture and 3D cell cultures benzene sensitivity. ⺠Carried out up to 20 days in vitro exposure studies. ⺠Validated A549 cell hanging drop toluene and xylene exposure EC50 value with published static apical air exposure method.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Health and Safety
Authors
Faye F. Liu, Cheng Peng, Beate I. Escher, Emmanuelle Fantino, Cindy Giles, Stephen Were, Lesley Duffy, Jack C. Ng,