Modulation of in vitro phagocytic uptake and immunogenicity potential of modified Herceptin®-conjugated PLGA-PEG nanoparticles for drug delivery

Article ID	Journal	Published Year	Pages	File Type
6980711	Colloids and Surfaces B: Biointerfaces	2018	31 Pages	PDF

Keywords

GM-CSF PBMC EDC HCl DCM IL-4 TFA TOF DCs NHS PLGA NPH granulocyte-macrophage colony stimulating factor 7-AAD 7-amino-actinomycin D N-hydroxysuccinimide PLGA-PEG TBTA Herceptin®tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine FBS DMF HER2 PBS FACS IL-6 DLS 1-Ethyl-3-(3-dimethylaminopropyl)-carbodiimide 1H NMR BSA NPs bovine serum albumin EDTA Ethylenediaminetetraacetic acid Trifluoroacetic acid hydrochloric acid Immunogenicity Tem Interleukin 4 interleukin 6 tumor necrosis factor alpha Cellular uptake fluorescent activated cell sorting Dichloromethane Time-of-Flight fetal bovine serum peripheral blood mononuclear cells Dendritic cells TNF-α Phosphate buffered saline lactate dehydrogenase LDH matrix assisted laser desorption/ionization MALDI Transmission electron microscopy Nanoparticles Nitric oxide Dynamic Light Scattering proton nuclear magnetic resonance polyethylene glycol PEG Human epidermal growth factor receptor 2

Related Topics

Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry

Modulation of in vitro phagocytic uptake and immunogenicity potential of modified Herceptin®-conjugated PLGA-PEG nanoparticles for drug delivery

Authors

Apurva Badkas, Evan Frank, Zilan Zhou, Mina Jafari, Harish Chandra, Vishnu Sriram, Joo-Youp Lee, Jagjit S. Yadav,