| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6981570 | Colloids and Surfaces B: Biointerfaces | 2015 | 8 Pages |
Abstract
- LFC131 peptide (d-Tyr-Arg-Arg-2-Nal-Gly), an inhibitor of CXCR4-ligand binding, is a low molecular weight CXCR4 antagonist.
- A novel LFC131 peptide surface conjugated O-CMC NP to target CXCR4 over expressed A549 lung cancer cells.
- Targeted NPs induced a greater apoptosis and caspase-3 activity in A549 cancer cells.
- Present nanoplatform could facilitate a treatment protocol for CXCR4 overexpressing A549 lung cancer cells.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Ruo-Tian Wang, Xiu-Yi Zhi, Shu-Yang Yao, Yi Zhang,