Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6981603 | Colloids and Surfaces B: Biointerfaces | 2015 | 8 Pages |
Abstract
- Poloxamine-DPPC interactions are stronger at low pressure and low lipid proportion.
- Cholesterol favors interaction with poloxamines having large PEO blocks.
- Hydrophobic copolymers with short PEO blocks expand lipid monolayer surface area.
- Poloxamines with long PEO blocks cause monolayer contraction and cell sealing.
- Long PEOs protect intact and cholesterol-depleted erythrocytes against haemolysis.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Isabel Sandez-Macho, Matilde Casas, Emilio V. Lage, M. Isabel Rial-Hermida, Angel Concheiro, Carmen Alvarez-Lorenzo,