| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6981612 | Colloids and Surfaces B: Biointerfaces | 2015 | 34 Pages |
Abstract
- Gene carriers with two types of degradable bonds (ester and SS) has been studied.
- The pH plays a crucial role in both the DNA complexation and release processes.
- At physiological pH, the ester bond hydrolysis is predominant.
- Working at acid pH is recommendable for the synthesis and storage of these polyplexes.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Azahara Rata-Aguilar, Nathaly Segovia-Ramos, Ana Belén Jódar-Reyes, VÃctor Ramos-Pérez, Salvador Borrós, Antonio MartÃn-RodrÃguez, Juan Luis Ortega-Vinuesa,