Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6981628 | Colloids and Surfaces B: Biointerfaces | 2015 | 9 Pages |
Abstract
- A novel metal ion-assisted drug-loading model was developed to improve drug-loading efficiency.
- FT-IR, Raman, fluorescence analyses were used to study DPPC:M2+ drug-loading liposome.
- The mechanism of higher drug encapsulation efficiency was clarified.
- The cell cytotoxicity of metal ion-assisted drug-loading liposomes was increased.
Keywords
DSCMALAASPBSDMEMRPMIDPPC1,2-dipalmitoyl-sn-glycero-3-phosphocholineDMSODulbecco's modified Eagle's mediumMTTAtomic absorption spectrophotometryEncapsulation efficiencyEnzyme-linked immunosorbent assayELISAThermosensitivityDimethylsulfoxideCytotoxicitycisplatinFT-IRFourier-transform infraredLiposomeRoswell Park Memorial InstitutePhosphate-buffered salineDifferential scanning calorimetrycholesterol
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Hong Liu, Yongle Zhang, Yazhu Han, Sha Zhao, Lu Wang, Zhaoxin Zhang, Jing Wang, Jianxin Cheng,