Article ID Journal Published Year Pages File Type
6981898 Colloids and Surfaces B: Biointerfaces 2015 8 Pages PDF
Abstract

- Silicone oils facilitate HSA denaturation in aqueous solutions.
- Low molecular weight silicones are particularly effective at facilitating protein denaturation and aggregation.
- Silicone surfactants facilitate emulsification, but not denaturation.
- The presence of small quantities of low molecular weight silicones in certain lots of silicone oil syringe lubricants may lead to the formation of veils in the syringe.
Keywords
Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
Preview
Low molecular weight silicones particularly facilitate human serum albumin denaturation
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