| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6982272 | Colloids and Surfaces B: Biointerfaces | 2015 | 11 Pages |
Abstract
- HBsAg/mannose-PEG-cholesterol/MPC/lipid A-liposomes (HBsAg-MLLs) were prepared.
- The pro-HBsAg-MLLs microneedle arrays (proHMAs) were constructed.
- The proHMAs were stable and applicable in the controlled temperature chain (CTC).
- The proHMAs given to mice via oral mucosa induced robust systemic/mucosal responses.
- Robust Th1/Th2 responses prove the proHMAs a therapeutic/prophylactic HBV vaccine.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Ting Wang, Yuanyuan Zhen, Xiaoyu Ma, Biao Wei, Shuqin Li, Ning Wang,