| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6982305 | Colloids and Surfaces B: Biointerfaces | 2015 | 8 Pages |
Abstract
- Multifunctional drug nanocarriers were synthesized using PAMAM, βCD, PEG and cyclic RGD peptide.
- Doxorubicin (Dox) was effectively encapsulated in the nanoparticles via an inclusion complex.
- The cellular uptake of cRGD-conjugated nanopartilces was higher than that of non-targeted nanoparticles.
- The anti-proliferative effect of targeted Dox was superior to that of non-targeted Dox.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Manju Saraswathy, Gavin T. Knight, Srikanth Pilla, Randolph S. Ashton, Shaoqin Gong,