| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6982367 | Colloids and Surfaces B: Biointerfaces | 2014 | 10 Pages |
Abstract
- NVP-loaded PEO-PPO-PEO polymeric micelles were successfully prepared.
- Addition of pharmaceutical cosolvents (Gly, PG, PEG 400) increased the micellar size and NVP solubility.
- PG and PEG 400 (40% v/v, ratio 1:1) were the best combination to optimize the micellar systems.
- Polymeric micelles presented better pharmacokinetic parameters than Viramune®.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Marcela A. Moretton, Laura Cohen, Leandro Lepera, Ezequiel Bernabeu, Carlos Taira, Christian Höcht, Diego A. Chiappetta,