Article ID Journal Published Year Pages File Type
6982484 Colloids and Surfaces B: Biointerfaces 2014 10 Pages PDF
Abstract

- Cubic and lamellar mesophases were characterized as transdermal drug delivery vehicles.
- Sodium diclofenac stabilizes, while celecoxib disturbs, the nanostructure self-assembly.
- The cubic system releases 1.5-fold higher amounts of sodium diclofenac than the lamellar.
- Celecoxib release is not affected from the water content; the drugs diffuse differently.
- The diffusion kinetics might be controlled by manipulating the mesophase composition.
Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
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