Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6982484 | Colloids and Surfaces B: Biointerfaces | 2014 | 10 Pages |
Abstract
- Cubic and lamellar mesophases were characterized as transdermal drug delivery vehicles.
- Sodium diclofenac stabilizes, while celecoxib disturbs, the nanostructure self-assembly.
- The cubic system releases 1.5-fold higher amounts of sodium diclofenac than the lamellar.
- Celecoxib release is not affected from the water content; the drugs diffuse differently.
- The diffusion kinetics might be controlled by manipulating the mesophase composition.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Marganit Cohen-Avrahami, Alexander I. Shames, M. Francesca Ottaviani, Abraham Aserin, Nissim Garti,