Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6982600 | Colloids and Surfaces B: Biointerfaces | 2014 | 10 Pages |
Abstract
- Albumin (BSA) microparticles were obtained in a W/O emulsion without and with PVA.
- BSA played a role as a surface active agent for W/O emulsion, replacing PVA.
- The microparticles showed a two-stage drug release profile at pH 2, 6 and 10.
- The two-step release mechanism is a characteristic of the BSA microparticles.
- The second release stage is a contribution of the matrix erosion.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Danielly L.A. Sitta, Marcos R. Guilherme, Elisangela P. da Silva, Artur J.M. Valente, Edvani C. Muniz, Adley F. Rubira,