| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6982609 | Colloids and Surfaces B: Biointerfaces | 2014 | 34 Pages |
Abstract
- TPGS was employed to improve the entrapment of dorzolamide hydrochloride into NPs.
- Effect of excipients and process variables on size and entrapment was assessed.
- Comparative transcorneal permeation as well as corneal uptake was performed.
- Reduction in corneal clearance as well as naso-lachrymal drainage was achieved.
- NPs showed better intraocular pressure lowering potential than drug solution.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Musarrat H. Warsi, Mohammed Anwar, Vaidehi Garg, Gaurav K. Jain, Sushama Talegaonkar, Farhan J. Ahmad, Roop K. Khar,