Article ID Journal Published Year Pages File Type
6982658 Colloids and Surfaces B: Biointerfaces 2014 9 Pages PDF
Abstract

- “Stealth” and glycotargeted cationic liposomes for ASGP-R targeting.
- PEGylation greatly reduced liposome and lipoplex size.
- Higher PEGylated lipoplexes show superior transfection efficiency in vitro.
- Density of PEG and lipoplex N/P (+:−) ratio strongly affect transfection levels.
- Specific ASGP-R mediated gene transfection was confirmed.
Keywords
Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
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PEGylated galactosylated cationic liposomes for hepatocytic gene delivery
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