Article ID Journal Published Year Pages File Type
6982698 Colloids and Surfaces B: Biointerfaces 2014 9 Pages PDF
Abstract

- Random copolymer synthesis of PLGA and BPEI for MTX conjugation by DCC/NHS chemistry.
- Preparation of nanomicelles of 5-FU-PBP-MTX with ultimate desired properties.
- Superior 5-FU entrapment in PBP-MTX nanomicelles.
- High amount of cellular uptake and cytotoxicity exhibited by the nanomicelles in vitro.
Keywords
Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
Preview
Dual drug delivery of 5-fluorouracil (5-FU) and methotrexate (MTX) through random copolymeric nanomicelles of PLGA and polyethylenimine demonstrating enhanced cell uptake and cytotoxicity
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