| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6983048 | Colloids and Surfaces B: Biointerfaces | 2014 | 8 Pages |
Abstract
- We synthesized targeting ligand-modified polymeric prodrugs (TFPXPEG).
- TFPXPEG showed dramatically increased solubility against aqueous solution better than free paclitaxel.
- In vitro and in vivo evaluation, TFPXPEG inhibited tumor growth and enhanced therapeutic efficacy.
- The synthesized TFPXPEG has potential to be used as tumor targeting polymeric prodrugs.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Joung-Pyo Nam, Jun-Kyu Park, Dong-Hee Son, Tae-Hun Kim, Sun-Jeong Park, Seong-Cheol Park, Changyong Choi, Mi-Kyeong Jang, Jae-Woon Nah,