Intracellular delivery and activation of the genetically encoded photosensitizer Killer Red by quantum dots encapsulated in polymeric micelles

- Killer Red genetically encoded photosensitizer selectively activated by green light.
- Killer Red generates ROS upon activation that damages the cell and trigger cell death.
- Polymeric micelle-QDots were prepared to deliver the Killer Red to cancer cells.
- Blue light activates QDots which emits locally in green wavelength inside the cells.
- PPP-QDot delivers Killer Red plasmid and activates the protein intracellularly.