| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6983280 | Colloids and Surfaces B: Biointerfaces | 2014 | 9 Pages |
Abstract
- Docetaxel-conjugated PLA-PEG-FOL micelles were successfully synthesized.
- The micelles showed a controlled drug release behavior due to the presence of hydrazone linkage between the polymer and the drug.
- In vitro cytotoxicity of both free docetaxel and its micellar formulations against SKOV3 cell line after 72Â h increased in a dose-dependent manner as measured with MTT, neutral red and LDH assays.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Zahra Hami, Mohsen Amini, Mahmoud Ghazi-Khansari, Seyed Mehdi Rezayat, Kambiz Gilani,