| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6983297 | Colloids and Surfaces B: Biointerfaces | 2014 | 9 Pages |
Abstract
- We investigate the cytotoxicity of core-shell MPS and colloidal silica particles.
- Core-shell MPS particles deliver less cytotoxicity than the nonporous counterparts.
- Core-shell MPS induce lower expression of the pro-inflammatory cytokines.
- Core-shell MPS show no effect on the activation of MAPKs, while colloidal ones do.
- The abundant proteins of the corona inhibit toxicity at the MPS-cellular interface.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Jie Wang, Yuqing Shen, Ling Bai, Dan Lv, Aifeng Zhang, Fengqin Miao, Meng Tang, Jianqiong Zhang,