| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6983373 | Colloids and Surfaces B: Biointerfaces | 2014 | 7 Pages |
Abstract
- Stimuli-responsive magnetoliposomes (dMLs) were designed for low dose chemotherapy.
- SPIO nanoparticles provided a bilayer trigger for intracellular doxorubicin release.
- High dML uptake was observed in Huh-7 cell line in vitro.
- dMLs exhibited low cytotoxicity unless activated by an external RF field.
- Huh-7 treatment was due to doxorubicin release and not local hyperthermia.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Yanjing Chen, Yuan Chen, Da Xiao, Arijit Bose, Ruitang Deng, Geoffrey D. Bothun,